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TitleCrystal structure of human V122I transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound
Journal, issue, pagesTo Be Published
Publish dateOct 23, 2024 (structure data deposition date)
AuthorsVarejao, N. / Pinheiro, F. / Pallares, I. / Ventura, S. / Reverter, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.67 - 1.7 Å
Structure data

PDB-9h5x:
Crystal structure of human V122I transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-9h5y:
Crystal structure of human V30M transthyretin in complex with (3,4-dihydroxy-5-nitrophenyl)-(3-fluoro-5-hydroxyphenyl)methanone compound
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

Chemicals

ChemComp-AQI:
(3-fluoranyl-5-oxidanyl-phenyl)-[3-nitro-4,5-bis(oxidanyl)phenyl]methanone

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT / T4 binding protein / Amyloid / Natural mutation / Inhibitor compound

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