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TitleBiochemical and structural insights into the auto-inhibited state of Mical1 and its activation by Rab8
Journal, issue, pagesElife, Year 2024
Publish dateJul 8, 2024 (structure data deposition date)
AuthorsRai, A. / Janning, P. / Vetter, I.R. / Goody, R.S.
External linksElife / Search PubMed
MethodsX-ray diffraction
Resolution1.8 - 2.05 Å
Structure data

PDB-9g0c:
Structure of human Mical1 bMERB_V978A_V985A domain:Rab10 complex.
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-9g0d:
Structure of human Mical1 bMERB_V978A domain:Rab10 complex.
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

Chemicals

ChemComp-GNP:
PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER / GppNHp, GMPPNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsENDOCYTOSIS / Mical / Rab GTPase / Complex / F-actin / Oxidation

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