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TitleGalectin-8N-Selective 4-Halophenylphthalazinone-Galactals Double pi-Stack in a Unique Pocket.
Journal, issue, pagesAcs Med. Chem. Lett., Vol. 15, Page 1319-1324, Year 2024
Publish dateJul 2, 2024 (structure data deposition date)
Authorsvan Klaveren, S. / Hassan, M. / Hakansson, M. / Johnsson, R.E. / Larsson, J. / Jakopin, Z. / Anderluh, M. / Leffler, H. / Tomasic, T. / Nilsson, U.J.
External linksAcs Med. Chem. Lett. / PubMed:39140038
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-9fxz:
Galectin-8 N-terminal carbohydrate recognition domain in complex with 4-(bromophenyl)phthalazinone D-galactal ligand
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals


ChemComp, No image

ChemComp-V19:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Galectin / phthalazinone / inhibitor / sugar binding protein

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