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TitleCrystal structure of Pyrococcus furiosus dolichylphosphate mannose synthase in complex with substrates (GDP-Man and DolP) and traces of a flipped glycolipid product (DolP-Man)
Journal, issue, pagesTo be published
Publish dateMar 16, 2024 (structure data deposition date)
AuthorsGandini, R. / Keskitalo, M. / Reichenbach, T. / Divne, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-9ep0:
Dolichyl phosphate mannose synthase in complex with donor (GDP-Man) and traces of acceptor (Dol55P) and product (Dol55P-Man)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-GDD:
GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE

ChemComp-MG:
Unknown entry

ChemComp-EFS:
ETHYL DIHYDROGEN PHOSPHATE

ChemComp-MJC:
dolichyl phosphate mannose

Source
  • pyrococcus furiosus dsm 3638 (archaea)
KeywordsTRANSFERASE / Dolichyl phosphate mannose synthase / enzyme / integral membrane protein / protein glycosylation / glycosylphosphatidylinositol synthesis / GDP-mannose / dolichyl monophosphate / dolichol monophosphate mannose / donor-acceptor and product complex

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