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TitleComplement Evasion by Blocking Activation of the C1r Zymogen
Journal, issue, pagesTo Be Published
Publish dateDec 2, 2024 (structure data deposition date)
AuthorsDuan, H. / Geisbrecht, B.V.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution3.1 - 3.28 Å
Structure data

PDB-9ekd:
Structure of a C1r Zymogen Fragment Bound to SALO
Method: X-RAY DIFFRACTION / Resolution: 3.28 Å

PDB-9eke:
Structure of a C1r Zymogen Fragment Bound to SALO, Y51F Mutant
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Source
  • lutzomyia longipalpis (insect)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HYDROLASE / complement system / C1r / zymogen / inhibitor

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