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TitleIn vivo functional profiling and structural characterisation of the human Glp1r A316T variant
Journal, issue, pagesTo Be Published
Publish dateOct 22, 2024 (structure data deposition date)
AuthorsEid LI / Deane-Alder K / Rujan R-M / Mariam Z / Oqua AI / Manchanda Y / Belousoff MJ / Serna JB / Sloop KW / Rutter GA ...Eid LI / Deane-Alder K / Rujan R-M / Mariam Z / Oqua AI / Manchanda Y / Belousoff MJ / Serna JB / Sloop KW / Rutter GA / Montoya A / Withers DJ / Millership SJ / Bouzakri K / Jones B / Reynolds CA / Sexton PM / Deganutti G / Wootten DL / Tomas A
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.3 Å
Structure data

47447

9e2a

EMDB-47447, PDB-9e2a:
Glucagon Like Peptide Receptor-1 (GLP1R) A316T mutant with GLP-1 peptide. Dominant negative Gs complex.
Method: EM (single particle) / Resolution: 3.3 Å

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsMEMBRANE PROTEIN / GPCR / GLP1 / GLP-1R

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