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Structure paper

TitleCryo-EM structures of human ClpXP reveal mechanisms of assembly and proteolytic activation
Journal, issue, pagesNat Commun, Vol. 17, Page 1064, Year 2026
Publish dateOct 8, 2024 (structure data deposition date)
AuthorsChen W / Lander GC / Yang J
External linksNat Commun / Search PubMed
MethodsEM (single particle)
Resolution3.2 Å
Structure data

47226

9dvy

EMDB-47226, PDB-9dvy:
Human mitochondrial ClpX with endogenous substrate
Method: EM (single particle) / Resolution: 3.2 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / Mitochondrial protein / AAA+ ATPase

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