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TitleA molecular basis underpinning TRBV28 + T-cell receptor recognition of MR1-antigen.
Journal, issue, pagesJ. Biol. Chem., Vol. 301, Page 110416-110416, Year 2025
Publish dateMay 24, 2024 (structure data deposition date)
AuthorsAwad, W. / Gherardin, N.A. / Ciacchi, L. / Keller, A.N. / Liu, L. / Fairlie, D.P. / McCluskey, J. / Godfrey, D.I. / Rossjohn, J.
External linksJ. Biol. Chem. / PubMed:40570962
MethodsX-ray diffraction
Resolution3.1 Å
Structure data

PDB-9bys:
Structure of human MAIT BV28 TCR in complex with human MR1-5-OP-RU
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-Q87:
1-deoxy-1-({2,6-dioxo-5-[(E)-(2-oxopropylidene)amino]-1,2,3,6-tetrahydropyrimidin-4-yl}amino)-D-ribitol

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / antigen presentation / MAIT cells / T cell receptor / MR1

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