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-Structure paper
Title | Fragment-Based Screen of SARS-CoV-2 Papain-like Protease (PL pro ). |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 15, Page 1351-1357, Year 2024 |
Publish date | May 11, 2024 (structure data deposition date) |
Authors | Taylor, A.J. / Amporndanai, K. / Rietz, T.A. / Zhao, B. / Thiruvaipati, A. / Wei, Q. / South, T.M. / Crow, M.M. / Apakama, C. / Sensintaffar, J.L. ...Taylor, A.J. / Amporndanai, K. / Rietz, T.A. / Zhao, B. / Thiruvaipati, A. / Wei, Q. / South, T.M. / Crow, M.M. / Apakama, C. / Sensintaffar, J.L. / Phan, J. / Lee, T. / Fesik, S.W. |
External links | Acs Med. Chem. Lett. / PubMed:39140055 |
Methods | X-ray diffraction |
Resolution | 1.8 - 2.6 Å |
Structure data | PDB-9brv: PDB-9brw: PDB-9brx: |
Chemicals | PDB-1ask: ChemComp-ZN: ChemComp-SO4: ChemComp-CL: ChemComp-HOH: PDB-1arl: PDB-1asl: |
Source |
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Keywords | VIRAL PROTEIN / HYDROLASE / PLpro / SARS-CoV-2 / drug discovery / inhibitor |