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-Structure paper
Title | Tri-complex of Compound-12, KRAS G12C, and CypA |
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Journal, issue, pages | To be published |
Publish date | Apr 18, 2024 (structure data deposition date) |
Authors | Jiang, J. / Jiang, L. / Maldonato, B.J. / Wang, Y. / Holderfield, M. / Aronchik, I. / Winters, I.P. / Salman, Z. / Blaj, C. / Menard, M. ...Jiang, J. / Jiang, L. / Maldonato, B.J. / Wang, Y. / Holderfield, M. / Aronchik, I. / Winters, I.P. / Salman, Z. / Blaj, C. / Menard, M. / Brodbeck, J. / Chen, Z. / Wei, X. / Rosen, M.J. / Gindin, Y. / Lee, B.J. / Evans, J.W. / Chang, S. / Wang, Z. / Seamon, K.J. / Parsons, D. / Cregg, J. / Marquez, A. / Tomlinson, A.C.A. / Yano, J.K. / Knox, J.E. / Quintana, E. / Aguirre, A.J. / Arbour, K.C. / Reed, A. / Gustafson, W.C. / Gill, A.L. / Koltun, E.S. / Wildes, D. / Smith, J.A.M. / Singh, M. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.26 Å |
Structure data | PDB-9bfy: |
Chemicals | ChemComp-GNP: PDB-1aol: ChemComp-CL: ChemComp-MG: ChemComp-HOH: |
Source |
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Keywords | SIGNALING PROTEIN/INHIBITOR / inhibitor / complex / small GTPase / cancer / tricomplex / SIGNALING PROTEIN-INHIBITOR complex / SIGNALING PROTEIN |