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TitleCrystallographic analysis of MitM, which catalyzes the post-mitosane modification in mitomycin biosynthesis
Journal, issue, pagesTo Be Published
Publish dateApr 28, 2024 (structure data deposition date)
AuthorsXia, M. / Dong, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.66 - 2.8 Å
Structure data

PDB-8zc7:
Crystallographic analysis of MitM, which catalyzes the post-mitosane modification in mitomycin biosynthesis
Method: X-RAY DIFFRACTION / Resolution: 2.66 Å

PDB-8zc8:
The structure of MitM and mitomycin A with SAH in mitomycin
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

ChemComp-MQA:
[(1aS,8S,8aR,8bS)-6,8a-dimethoxy-5-methyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate

Source
  • streptomyces caespitosus (bacteria)
KeywordsTRANSFERASE / SAM-dependent methyltransferase

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