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TitleA fluorescent STING ligand sensor for high-throughput screening of compounds that can enhance tumor immunotherapy.
Journal, issue, pagesCell Rep Methods, Vol. 5, Page 101106-101106, Year 2025
Publish dateApr 14, 2024 (structure data deposition date)
AuthorsSun, P. / Wang, B. / Liu, C. / Wang, Z. / Liu, Y. / Qiao, Y.B. / Li, X.
External linksCell Rep Methods / PubMed:40669456
MethodsX-ray diffraction
Resolution2.4 Å
Structure data

PDB-8z37:
Crystal structure of human STING ligand binding domain.
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-CA:
Unknown entry

ChemComp-Y4T:
(1P)-3',5-di(prop-2-en-1-yl)[1,1'-biphenyl]-2,4'-diol

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / cGAMP binding protein

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