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-Structure paper
Title | Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by retatrutide. |
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Journal, issue, pages | Cell Discov, Vol. 10, Issue 1, Page 77, Year 2024 |
Publish date | Jul 17, 2024 |
Authors | Wenzhuo Li / Qingtong Zhou / Zhaotong Cong / Qingning Yuan / Wenxin Li / Fenghui Zhao / H Eric Xu / Li-Hua Zhao / Dehua Yang / Ming-Wei Wang / |
External links | Cell Discov / PubMed:39019866 / PubMed Central |
Methods | EM (single particle) |
Resolution | 2.68 - 3.26 Å |
Structure data | EMDB-39621, PDB-8yw3: EMDB-39622, PDB-8yw4: EMDB-39623, PDB-8yw5: |
Source |
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Keywords | STRUCTURAL PROTEIN / G protein-coupled receptor / ligand recognition / receptor activation / unimolecular agonist / retatrutide |