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TitleStructural insights into phosphatidylethanolamine N -methyltransferase PmtA mediating bacterial phosphatidylcholine synthesis.
Journal, issue, pagesSci Adv, Vol. 10, Page eadr0122-eadr0122, Year 2024
Publish dateMar 22, 2024 (structure data deposition date)
AuthorsSalsabila, S.D. / Kim, J.
External linksSci Adv / PubMed:39356767
MethodsX-ray diffraction
Resolution1.46 Å
Structure data

PDB-8ys9:
Crystal structure of Phosphatidylethanolamine N-methyltransferase from R. thermophilum complexed with DMPE and SAH
Method: X-RAY DIFFRACTION / Resolution: 1.46 Å

Chemicals

ChemComp-SAH:
S-ADENOSYL-L-HOMOCYSTEINE

PDB-1l1h:
Crystal Structure of the Quadruplex DNA-Drug Complex

ChemComp-SO4:
SULFATE ION

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-LMT:
DODECYL-BETA-D-MALTOSIDE / detergent*YM

ChemComp-HOH:
WATER

Source
  • rubellimicrobium thermophilum dsm 16684 (bacteria)
KeywordsTRANSFERASE / Phosphatidylethanolamine / Phosphatidylcholine / Bacterial phosphatidylcholine biosynthesis / Peripheral membrane protein / SAM-dependent methyltransferase / MEMBRANE PROTEIN / PmtA

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