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TitleCarboxymethylcytosine is a natural base modification and a handle for bacteriophage DNA hypermodification.
Journal, issue, pagesNat Commun, Vol. 17, Page 281-281, Year 2025
Publish dateFeb 23, 2024 (structure data deposition date)
AuthorsYang, Q. / Zhang, L. / Liang, Y. / Ma, H. / Song, L. / Luo, L. / Tan, J. / Hu, Y. / Ma, K. / Chen, Y. ...Yang, Q. / Zhang, L. / Liang, Y. / Ma, H. / Song, L. / Luo, L. / Tan, J. / Hu, Y. / Ma, K. / Chen, Y. / Tong, Y. / Zhang, C. / Zhao, S. / Wang, M. / Wei, Y. / Zhang, Y.
External linksNat Commun / PubMed:41354841
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-8yf3:
DNA cytosine C5-carboxymethyltransferase in complex with Cx-SAM
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-GEK:
(2S)-4-[{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}(carboxylatomethyl)sulfonio]

ChemComp-HOH:
WATER

Source
  • synechococcus phage s-b43 (virus)
KeywordsTRANSFERASE / DNA cytosine-5-carboxymethyltransferase / Carboxy-SAM

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