+Search query
-Structure paper
Title | Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design. |
---|---|
Journal, issue, pages | J. Med. Chem., Vol. 67, Page 2690-2711, Year 2024 |
Publish date | Sep 28, 2023 (structure data deposition date) |
![]() | Gimenez, L.E. / Martin, C. / Yu, J. / Hollanders, C. / Hernandez, C.C. / Wu, Y. / Yao, D. / Han, G.W. / Dahir, N.S. / Wu, L. ...Gimenez, L.E. / Martin, C. / Yu, J. / Hollanders, C. / Hernandez, C.C. / Wu, Y. / Yao, D. / Han, G.W. / Dahir, N.S. / Wu, L. / Van der Poorten, O. / Lamouroux, A. / Mannes, M. / Zhao, S. / Tourwe, D. / Stevens, R.C. / Cone, R.D. / Ballet, S. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.9 - 3.3 Å |
Structure data | ![]() PDB-8wky: ![]() PDB-8wkz: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-OLA: ![]() ChemComp-HOH: |
Source |
|
![]() | MEMBRANE PROTEIN / Ca++ cofactor / GPCR / PGS fusion / LCP |