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-Structure paper
Title | Development of Benziodarone Analogues with Enhanced Potency for Selective Binding to Transthyretin in Human Plasma. |
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Journal, issue, pages | J. Med. Chem., Vol. 67, Page 6987-7005, Year 2024 |
Publish date | Sep 22, 2023 (structure data deposition date) |
Authors | Mizuguchi, M. / Nakagawa, Y. / Yokoyama, T. / Okada, T. / Fujii, K. / Takahashi, K. / Luan, N.N.T. / Nabeshima, Y. / Kanamitsu, K. / Nakagawa, S. ...Mizuguchi, M. / Nakagawa, Y. / Yokoyama, T. / Okada, T. / Fujii, K. / Takahashi, K. / Luan, N.N.T. / Nabeshima, Y. / Kanamitsu, K. / Nakagawa, S. / Yamakawa, S. / Ueda, M. / Ando, Y. / Toyooka, N. |
External links | J. Med. Chem. / PubMed:38670538 |
Methods | X-ray diffraction |
Resolution | 1.508 - 1.801 Å |
Structure data | PDB-8wgs: PDB-8wgt: PDB-8wgu: |
Chemicals |
ChemComp-WGH: ChemComp-HOH:
ChemComp-WGJ:
ChemComp-WH0: |
Source |
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Keywords | TRANSPORT PROTEIN / Transthyretin / amyloidosis / inhibitor / benziodarone derivative |