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Structure paper

TitleStructural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds
Journal, issue, pagesJ. Mol. Struct., Vol. 1339, Page 142179-, Year 2025
Publish dateJan 13, 2024 (structure data deposition date)
AuthorsPark, H. / Feng, Y.
External linksJ. Mol. Struct. / Search PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-8vnx:
A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-WHQ:
(4P)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1H-indazol-1-yl]-N-methylthiophene-2-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / C-Jun terminal kinase 3 / JNK3 / p38 alpha / Kinase / selectivity

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