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TitleStructural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.
Journal, issue, pagesJ. Allergy Clin. Immunol., Vol. 154, Page 447-457, Year 2024
Publish dateJan 8, 2024 (structure data deposition date)
AuthorsBall, A. / Khatri, K. / Glesner, J. / Vailes, L.D. / Wunschmann, S. / Gabel, S.A. / Mueller, G.A. / Zhang, J. / Peebles Jr., R.S. / Chapman, M.D. ...Ball, A. / Khatri, K. / Glesner, J. / Vailes, L.D. / Wunschmann, S. / Gabel, S.A. / Mueller, G.A. / Zhang, J. / Peebles Jr., R.S. / Chapman, M.D. / Smith, S.A. / Chruszcz, M. / Pomes, A.
External linksJ. Allergy Clin. Immunol. / PubMed:38697404
MethodsX-ray diffraction
Resolution2.508 - 3.05 Å
Structure data

PDB-8vk1:
X-ray crystal structure of human IgE 4C8 Fab complex with Der p 2.0103
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-8vk2:
X-ray crystal structure of human IgE 4C8 Fab
Method: X-RAY DIFFRACTION / Resolution: 2.508 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • dermatophagoides pteronyssinus (European house dust mite)
KeywordsALLERGEN/IMMUNE SYSTEM / dust mite allergy / house dust mite / Der p 2-IgE complex / Human IgE against Der p 2 / antibody-allergen complex / antibody-allergen interaction / ALLERGEN-IMMUNE SYSTEM complex / IMMUNE SYSTEM / IgE antibody / human immune system / human IgE antibody / anti Der p 2 antibody / IgE against dust mite

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