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TitleReversible male contraception by targeted inhibition of serine/threonine kinase 33.
Journal, issue, pagesScience, Vol. 384, Page 885-890, Year 2024
Publish dateDec 21, 2023 (structure data deposition date)
AuthorsKu, A.F. / Sharma, K.L. / Ta, H.M. / Sutton, C.M. / Bohren, K.M. / Wang, Y. / Chamakuri, S. / Chen, R. / Hakenjos, J.M. / Jimmidi, R. ...Ku, A.F. / Sharma, K.L. / Ta, H.M. / Sutton, C.M. / Bohren, K.M. / Wang, Y. / Chamakuri, S. / Chen, R. / Hakenjos, J.M. / Jimmidi, R. / Kent, K. / Li, F. / Li, J.Y. / Ma, L. / Madasu, C. / Palaniappan, M. / Palmer, S.S. / Qin, X. / Robers, M.B. / Sankaran, B. / Tan, Z. / Vasquez, Y.M. / Wang, J. / Wilkinson, J. / Yu, Z. / Ye, Q. / Young, D.W. / Teng, M. / Kim, C. / Matzuk, M.M.
External linksScience / PubMed:38781365
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-8vf6:
Crystal structure of Serine/threonine-protein kinase 33 (STK33) Kinase Domain in complex with inhibitor CDD-2211
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

PDB-1aay:
ZIF268 ZINC FINGER-DNA COMPLEX

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOSOLIC PROTEIN / Kinase / STK33

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