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-Structure paper
Title | Discovery of potent small-molecule inhibitors of lipoprotein(a) formation. |
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Journal, issue, pages | Nature, Vol. 629, Page 945-950, Year 2024 |
Publish date | Jun 30, 2023 (structure data deposition date) |
Authors | Diaz, N. / Perez, C. / Escribano, A.M. / Sanz, G. / Priego, J. / Lafuente, C. / Barberis, M. / Calle, L. / Espinosa, J.F. / Priest, B.T. ...Diaz, N. / Perez, C. / Escribano, A.M. / Sanz, G. / Priego, J. / Lafuente, C. / Barberis, M. / Calle, L. / Espinosa, J.F. / Priest, B.T. / Zhang, H.Y. / Nosie, A.K. / Haas, J.V. / Cannady, E. / Borel, A. / Schultze, A.E. / Sauder, J.M. / Hendle, J. / Weichert, K. / Nicholls, S.J. / Michael, L.F. |
External links | Nature / PubMed:38720069 |
Methods | X-ray diffraction |
Resolution | 1.07 - 2.01 Å |
Structure data | PDB-8tce: PDB-8v8z: PDB-8v9b: |
Chemicals |
ChemComp-HWF: ChemComp-HOH:
PDB-1aak: Unknown entry ChemComp-SO4: ChemComp-MG: PDB-1aam: |
Source |
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Keywords | LIPID BINDING PROTEIN / Complex / Inhibitor / LDL |