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TitlecryoEM structure of Komagataella pastoris Cytochrome c oxidase (9 subunits) in complex with human VMAT2 and Amphetamin
Journal, issue, pagesTo Be Published
Publish dateSep 26, 2023 (structure data deposition date)
AuthorsYe J / Liu B / Li W
External linksSearch PubMed
MethodsEM (single particle)
Resolution3.25 Å
Structure data

42133

8uco

EMDB-42133, PDB-8uco:
CryoEM structure of Komagataella pastoris Cytochrome c oxidase (9 subunits) in complex with human VMAT2 and Amphetamine
Method: EM (single particle) / Resolution: 3.25 Å

Chemicals

ChemComp-1WE:
(2S)-1-phenylpropan-2-amine

ChemComp-CU:
COPPER (II) ION

ChemComp-HEA:
HEME-A

ChemComp-CUA:
DINUCLEAR COPPER ION

ChemComp-PTY:
PHOSPHATIDYLETHANOLAMINE / phospholipid*YM

ChemComp-ZN:
Unknown entry

Source
  • homo sapiens (human)
  • komagataella pastoris (fungus)
KeywordsMEMBRANE PROTEIN / VMAT / SLC18 / vascular monoamine transporter / Cytochrome c oxidase-VMAT2 complex / Amphetamin

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