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Title | Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge. |
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Journal, issue, pages | Nat Commun, Vol. 15, Page 1553-1553, Year 2024 |
Publish date | Aug 31, 2023 (structure data deposition date) |
Authors | Hsieh, C.L. / Leist, S.R. / Miller, E.H. / Zhou, L. / Powers, J.M. / Tse, A.L. / Wang, A. / West, A. / Zweigart, M.R. / Schisler, J.C. ...Hsieh, C.L. / Leist, S.R. / Miller, E.H. / Zhou, L. / Powers, J.M. / Tse, A.L. / Wang, A. / West, A. / Zweigart, M.R. / Schisler, J.C. / Jangra, R.K. / Chandran, K. / Baric, R.S. / McLellan, J.S. |
External links | Nat Commun / PubMed:38378768 |
Methods | X-ray diffraction |
Resolution | 3.2 Å |
Structure data | PDB-8u1g: |
Chemicals | ChemComp-NAG: |
Source |
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Keywords | VIRAL PROTEIN / SARS-CoV-2 spike / S2-only antigen / prefusion-stabilized stem |