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Structure paper

TitleThe ICF syndrome protein CDCA7 harbors a unique DNA binding domain that recognizes a CpG dyad in the context of a non-B DNA.
Journal, issue, pagesSci Adv, Vol. 10, Page eadr0036-eadr0036, Year 2024
Publish dateJul 26, 2023 (structure data deposition date)
AuthorsHardikar, S. / Ren, R. / Ying, Z. / Zhou, J. / Horton, J.R. / Bramble, M.D. / Liu, B. / Lu, Y. / Coletta, L.D. / Shen, J. ...Hardikar, S. / Ren, R. / Ying, Z. / Zhou, J. / Horton, J.R. / Bramble, M.D. / Liu, B. / Lu, Y. / Coletta, L.D. / Shen, J. / Dan, J. / Zhang, X. / Cheng, X. / Chen, T.
External linksSci Adv / PubMed:39178265
MethodsX-ray diffraction
Resolution2.58 Å
Structure data

PDB-8tll:
CDCA7 (Mouse) Binds Non-B-form 26-mer DNA oligo
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsDNA BINDING PROTEIN/DNA / PROTEIN-DNA COMPLEX / DNA BINDING PROTEIN / zinc fingers / chromatin architecture / DNA BINDING PROTEIN-DNA complex

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