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-Structure paper
Title | Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining |
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Journal, issue, pages | To Be Published |
Publish date | Jun 12, 2023 (structure data deposition date) |
![]() | Hsiao, Y. / Lin, Z. / Du, C. / Echeverria, A. / Wallweber, H.A. / Aung, T. / Alberstein, R.G. / Shang, Y. / Seeger, F. / Watkins, A. ...Hsiao, Y. / Lin, Z. / Du, C. / Echeverria, A. / Wallweber, H.A. / Aung, T. / Alberstein, R.G. / Shang, Y. / Seeger, F. / Watkins, A. / Seshasayee, D. / Hansen, D.V. / Bolen, C. / Hsu, P.L. / Hotzel, I. |
![]() | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.9 - 2 Å |
Structure data | ![]() PDB-8t51: ![]() PDB-8t59: |
Chemicals | ![]() ChemComp-SO4: ![]() ChemComp-ZN: ![]() ChemComp-GOL: ![]() ChemComp-ACT: ![]() ChemComp-PEG: ![]() ChemComp-HOH: |
Source |
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![]() | PEPTIDE BINDING PROTEIN / Antibody / Fab / IMMUNE SYSTEM/PEPTIDE BINDING PROTEIN / complex / antigen / IMMUNE SYSTEM-PEPTIDE BINDING PROTEIN complex |