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Structure paper

TitleStructural analysis of light chain-driven bispecific antibodies targeting CD47 and PD-L1.
Journal, issue, pagesMabs, Vol. 16, Page 2362432-2362432, Year 2024
Publish dateJan 12, 2024 (structure data deposition date)
AuthorsMalinge, P. / Chauchet, X. / Bourguignon, J. / Bosson, N. / Calloud, S. / Bautzova, T. / Borlet, M. / Laursen, M. / Kelpsas, V. / Rose, N. ...Malinge, P. / Chauchet, X. / Bourguignon, J. / Bosson, N. / Calloud, S. / Bautzova, T. / Borlet, M. / Laursen, M. / Kelpsas, V. / Rose, N. / Gueneau, F. / Ravn, U. / Magistrelli, G. / Fischer, N.
External linksMabs / PubMed:38849989
MethodsX-ray diffraction
Resolution2 - 2.794 Å
Structure data

PDB-8rp8:
Structure of K2 Fab in complex with human CD47 ECD
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-8rpb:
Structure of S79 Fab in complex with IgV domain of human PD-L1
Method: X-RAY DIFFRACTION / Resolution: 2.794 Å

Chemicals

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-GOL:
GLYCEROL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Fab / glycoprotein

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