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-Structure paper
Title | Macrocyclic Oxindole Peptide Epoxyketones-A Comparative Study of Macrocyclic Inhibitors of the 20S Proteasome. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 15, Page 533-539, Year 2024 |
Publish date | Dec 15, 2023 (structure data deposition date) |
![]() | Gotz, M.G. / Godwin, K. / Price, R. / Dorn, R. / Merrill-Steskal, G. / Klemmer, W. / Hansen, H. / Produturi, G. / Rocha, M. / Palmer, M. ...Gotz, M.G. / Godwin, K. / Price, R. / Dorn, R. / Merrill-Steskal, G. / Klemmer, W. / Hansen, H. / Produturi, G. / Rocha, M. / Palmer, M. / Molacek, L. / Strater, Z. / Groll, M. |
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Methods | X-ray diffraction |
Resolution | 2.8 - 3.2 Å |
Structure data | ![]() PDB-8rhj: ![]() PDB-8rhk: ![]() PDB-8rhl: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-CL: ![]() ChemComp-HOH: ![]() ChemComp-MES: |
Source |
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![]() | HYDROLASE / Proteasome / Epoxomicin / TMC-95A / Carfilzomib / Macrocycle / Binding Analysis |