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-Structure paper
Title | Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer. |
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Journal, issue, pages | J. Med. Chem., Vol. 67, Page 9374-9388, Year 2024 |
Publish date | Nov 23, 2023 (structure data deposition date) |
Authors | Zetterberg, F.R. / Peterson, K. / Nilsson, U.J. / Andreasson Dahlgren, K. / Diehl, C. / Holyer, I. / Hakansson, M. / Khabut, A. / Kahl-Knutson, B. / Leffler, H. ...Zetterberg, F.R. / Peterson, K. / Nilsson, U.J. / Andreasson Dahlgren, K. / Diehl, C. / Holyer, I. / Hakansson, M. / Khabut, A. / Kahl-Knutson, B. / Leffler, H. / MacKinnon, A.C. / Roper, J.A. / Slack, R.J. / Zarrizi, R. / Pedersen, A. |
External links | J. Med. Chem. / PubMed:38804039 |
Methods | X-ray diffraction |
Resolution | 1.54 Å |
Structure data | PDB-8r74: |
Chemicals |
ChemComp-YBC: ChemComp-HOH: |
Source |
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Keywords | SUGAR BINDING PROTEIN / galectin / ligand / thiogalactoside derivative |