+Search query
-Structure paper
Title | Structural basis of p53 inactivation by cavity-creating cancer mutations and its implications for the development of mutant p53 reactivators. |
---|---|
Journal, issue, pages | Cell Death Dis, Vol. 15, Page 408-408, Year 2024 |
Publish date | Oct 19, 2023 (structure data deposition date) |
Authors | Balourdas, D.I. / Markl, A.M. / Kramer, A. / Settanni, G. / Joerger, A.C. |
External links | Cell Death Dis / PubMed:38862470 |
Methods | X-ray diffraction |
Resolution | 1.38 - 2.1 Å |
Structure data | PDB-8qwk: PDB-8qwl: PDB-8qwm: PDB-8qwn: PDB-8qwo: PDB-8qwp: |
Chemicals | ChemComp-ZN: ChemComp-EDO: ChemComp-HOH: ChemComp-MLI: ChemComp-TLA: ChemComp-MG: ChemComp-CL: ChemComp-GOL: |
Source |
|
Keywords | DNA BINDING PROTEIN / tumor suppressor / transcription factor / cancer mutation / protein stability / conformational mutant |