+Search query
-Structure paper
Title | Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor. |
---|---|
Journal, issue, pages | Nat Commun, Vol. 15, Page 1173-1173, Year 2024 |
Publish date | Jun 19, 2023 (structure data deposition date) |
Authors | Sake, S.M. / Zhang, X. / Rajak, M.K. / Urbanek-Quaing, M. / Carpentier, A. / Gunesch, A.P. / Grethe, C. / Matthaei, A. / Ruckert, J. / Galloux, M. ...Sake, S.M. / Zhang, X. / Rajak, M.K. / Urbanek-Quaing, M. / Carpentier, A. / Gunesch, A.P. / Grethe, C. / Matthaei, A. / Ruckert, J. / Galloux, M. / Larcher, T. / Le Goffic, R. / Hontonnou, F. / Chatterjee, A.K. / Johnson, K. / Morwood, K. / Rox, K. / Elgaher, W.A.M. / Huang, J. / Wetzke, M. / Hansen, G. / Fischer, N. / Eleouet, J.F. / Rameix-Welti, M.A. / Hirsch, A.K.H. / Herold, E. / Empting, M. / Lauber, C. / Schulz, T.F. / Krey, T. / Haid, S. / Pietschmann, T. |
External links | Nat Commun / PubMed:38332002 |
Methods | X-ray diffraction |
Resolution | 2.289 Å |
Structure data | PDB-8phi: |
Chemicals | ChemComp-336: ChemComp-SO4: ChemComp-PG0: ChemComp-CA: ChemComp-HOH: |
Source |
|
Keywords | VIRAL PROTEIN / RSV F Glycoprotein / inhibitor |