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-Structure paper
Title | Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase. |
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Journal, issue, pages | Acs Med. Chem. Lett., Vol. 14, Page 1631-1639, Year 2023 |
Publish date | Jun 11, 2023 (structure data deposition date) |
Authors | Hoegenauer, K. / An, S. / Axford, J. / Benander, C. / Bergsdorf, C. / Botsch, J. / Chau, S. / Fernandez, C. / Gleim, S. / Hassiepen, U. ...Hoegenauer, K. / An, S. / Axford, J. / Benander, C. / Bergsdorf, C. / Botsch, J. / Chau, S. / Fernandez, C. / Gleim, S. / Hassiepen, U. / Hunziker, J. / Joly, E. / Keller, A. / Lopez Romero, S. / Maher, R. / Mangold, A.S. / Mickanin, C. / Mihalic, M. / Neuner, P. / Patterson, A.W. / Perruccio, F. / Roggo, S. / Scesa, J. / Schroder, M. / Shkoza, D. / Thai, B. / Vulpetti, A. / Renatus, M. / Reece-Hoyes, J.S. |
External links | Acs Med. Chem. Lett. / PubMed:38116426 |
Methods | X-ray diffraction |
Resolution | 1.3 - 2.714 Å |
Structure data | PDB-8pd4: PDB-8pd6: |
Chemicals | ChemComp-HOH: ChemComp-YCB: ChemComp-MG: ChemComp-CL: ChemComp-EDO: |
Source |
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Keywords | TRANSFERASE / E3 ligase / TRIM58 / PRY-SPRY |