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-Structure paper
Title | The reversible inhibitor SR-4835 binds Cdk12/cyclin K in a noncanonical G-loop conformation. |
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Journal, issue, pages | J. Biol. Chem., Vol. 300, Page 105501-105501, Year 2023 |
Publish date | May 31, 2023 (structure data deposition date) |
![]() | Schmitz, M. / Kaltheuner, I.H. / Anand, K. / Duster, R. / Moecking, J. / Monastyrskyi, A. / Duckett, D.R. / Roush, W.R. / Geyer, M. |
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Methods | X-ray diffraction |
Resolution | 2.68 Å |
Structure data | ![]() PDB-8p81: |
Chemicals | ![]() ChemComp-RMF: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSCRIPTION / Cyclin-dependent kinase / inhibitor / SR-4835 / Cdk12 / Cyclin K |