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Structure paper

TitleControlling the incorporation of fluorinated amino acids in human cells and its structural impact.
Journal, issue, pagesProtein Sci., Vol. 33, Page e4910-e4910, Year 2024
Publish dateMay 30, 2023 (structure data deposition date)
AuthorsCostantino, A. / Pham, L.B.T. / Barbieri, L. / Calderone, V. / Ben-Nissan, G. / Sharon, M. / Banci, L. / Luchinat, E.
External linksProtein Sci. / PubMed:38358125
MethodsX-ray diffraction
Resolution1.3 Å
Structure data

PDB-8p6u:
Human carbonic anhydrase II containing 5-fluorotryptophanes
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-8phl:
Human carbonic anhydrase II containing 4-fluorophenylalanine
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

PDB-8q0c:
Human carbonic anhydrase II containing 3-fluorotyrosine
Method: X-RAY DIFFRACTION / Resolution: 1.3 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MBO:
MERCURIBENZOIC ACID

ChemComp-BEZ:
BENZOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsLYASE / Human carbonic anhydrase II / hCAII / 5-fluorotryptophane / in-cell NMR / carbonic anhydrase / 4-fluorophenylalanine

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