+Search query
-Structure paper
Title | Structural Basis of gamma-secretase inhibition by anti-cancer clinical drugs |
---|---|
Journal, issue, pages | To Be Published |
Publish date | Aug 8, 2023 (structure data deposition date) |
Authors | Guo X / Li H / Kai U / Yan C / Lei J / Zhou R / Shi Y |
External links | Search PubMed |
Methods | EM (single particle) |
Resolution | 2.4 - 3.0 Å |
Structure data | EMDB-37107, PDB-8kcp: EMDB-37108, PDB-8kcs: EMDB-37109, PDB-8kct: EMDB-37110, PDB-8kcu: |
Chemicals | ChemComp-NAG: ChemComp-PC1:
ChemComp-N9C: ChemComp-CLR:
ChemComp-Q70:
ChemComp-O6U:
ChemComp-OL9: |
Source |
|
Keywords | MEMBRANE PROTEIN / Intramembrane protease / gamma-secretase / gamma-secretase inhibitor / MEMBRANE PROTEIN-HYDROLASE complex |