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-Structure paper
Title | Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 63, Page e202316394-e202316394, Year 2024 |
Publish date | May 17, 2023 (structure data deposition date) |
![]() | Tang, G. / Wang, W. / Zhu, C. / Huang, H. / Chen, P. / Wang, X. / Xu, M. / Sun, J. / Zhang, C.J. / Xiao, Q. ...Tang, G. / Wang, W. / Zhu, C. / Huang, H. / Chen, P. / Wang, X. / Xu, M. / Sun, J. / Zhang, C.J. / Xiao, Q. / Gao, L. / Zhang, Z.M. / Yao, S.Q. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.84647631109 - 2.90002335195 Å |
Structure data | ![]() PDB-8jf3: ![]() PDB-8jf4: ![]() PDB-8jg8: |
Chemicals | ![]()
ChemComp-C0N: ![]()
ChemComp-C74: |
Source |
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![]() | TRANSFERASE/Inhibitor / TRANSFERASE-Inhibitor complex / CYTOKINE / Lysine inhibitor / inhibitor kinase |