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Structure paper

TitleKlebsiella pneumoniae K2 capsular polysaccharide degradation by a bacteriophage depolymerase does not require trimer formation.
Journal, issue, pagesMbio, Vol. 15, Page e0351923-e0351923, Year 2024
Publish dateMar 15, 2023 (structure data deposition date)
AuthorsYe, T.J. / Fung, K.M. / Lee, I.M. / Ko, T.P. / Lin, C.Y. / Wong, C.L. / Tu, I.F. / Huang, T.Y. / Yang, F.L. / Chang, Y.P. ...Ye, T.J. / Fung, K.M. / Lee, I.M. / Ko, T.P. / Lin, C.Y. / Wong, C.L. / Tu, I.F. / Huang, T.Y. / Yang, F.L. / Chang, Y.P. / Wang, J.T. / Lin, T.L. / Huang, K.F. / Wu, S.H.
External linksMbio / PubMed:38349137
MethodsX-ray diffraction
Resolution1.38 - 2.17 Å
Structure data

PDB-8iq5:
Crystal structure of trimeric K2-2 TSP
Method: X-RAY DIFFRACTION / Resolution: 1.38 Å

PDB-8iq9:
Crystal structure of trimeric K2-2 TSP in complex with tetrasaccharide and octasaccharide
Method: X-RAY DIFFRACTION / Resolution: 1.58 Å

PDB-8iqe:
Crystal structure of tetrameric K2-2 TSP
Method: X-RAY DIFFRACTION / Resolution: 2.17 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-BCN:
BICINE / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-ACE:
ACETYL GROUP

ChemComp-EDO:
1,2-ETHANEDIOL

Source
  • klebsiella phage vlc6 (virus)
KeywordsHYDROLASE / bacteriophage / tailspike protein / Klebsiella pneumoniae K2

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