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Structure paper

TitleSmall peptide enhances the binding of nutline-3a to N-terminal domain of MdmX
Journal, issue, pagesTo Be Published
Publish dateFeb 7, 2023 (structure data deposition date)
AuthorsCheng, X.Y. / Wei, Q.Y. / Huang, Y. / Su, Z.D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.93 Å
Structure data

PDB-8ia5:
Small peptide enhances the binding of nutline-3a to N-terminal domain of MdmX
Method: X-RAY DIFFRACTION / Resolution: 1.93 Å

Chemicals

ChemComp-NUT:
4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one

ChemComp-O4B:
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsONCOPROTEIN / MdmX / p53 / Nutlin-3a / Enhancement

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