Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Journal, issue, pages	Blood, Vol. 143, Page 1825-1836, Year 2024
Publish date	Dec 10, 2022 (structure data deposition date)
Authors	Liu, J. / Li, S. / Wang, Q. / Feng, Y. / Xing, H. / Yang, X. / Guo, Y. / Sun, H. / Liu, X. / Yang, S. ...Liu, J. / Li, S. / Wang, Q. / Feng, Y. / Xing, H. / Yang, X. / Guo, Y. / Sun, H. / Liu, X. / Yang, S. / Mei, Z. / Zhu, Y. / Cheng, Z. / Chen, S. / Xu, M. / Zhang, W. / Wan, N. / Wang, J. / Ma, Y. / Zhang, S. / Luan, X. / Xu, A. / Li, L. / Wang, H. / Hong, Y. / Xue, H. / Yuan, X. / Hu, N. / Song, X. / Wang, Z. / Wang, L. / Liu, Y.
External links	Blood / PubMed:38211332
Methods	X-ray diffraction
Resolution	1.8 - 2.25 Å
Structure data	PDB-8hog: Crystal structure of Bcl-2 in complex with sonrotoclax Method: X-RAY DIFFRACTION / Resolution: 1.8 Å PDB-8hoh: Crystal structure of Bcl-2 G101V in complex with sonrotoclax Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-8hoi: Crystal structure of Bcl-2 D103Y in complex with sonrotoclax Method: X-RAY DIFFRACTION / Resolution: 2.25 Å
Chemicals	ChemComp-98I: ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide ChemComp-HOH: WATER ChemComp-FMT: FORMIC ACID
Source	homo sapiens (human)
Keywords	APOPTOSIS / Inhibitor