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-Structure paper
Title | Structural and mechanistic insights into cancer patient-derived mutations in Pyruvate Kinase muscle isoform 2 |
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Journal, issue, pages | To Be Published |
Publish date | Dec 5, 2022 (structure data deposition date) |
Authors | Upadhyay, S. / Kumar, A. / Patel, A.K. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.6 Å |
Structure data | PDB-8hmq: PDB-8hmr: PDB-8hms: PDB-8hmu: |
Chemicals | ChemComp-OXL: ChemComp-GOL: ChemComp-EDO: ChemComp-MG: ChemComp-FBP: ChemComp-HOH: ChemComp-PO4: |
Source |
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Keywords | TRANSFERASE / PKM2 / Hydroxylation / Kinase / Glycolysis / Tumour Promoting / Warburg Effect |