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-Structure paper
Title | A novel allosteric site employs a conserved inhibition mechanism in human kidney-type glutaminase. |
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Journal, issue, pages | Febs J., Vol. 290, Page 2437-2448, Year 2023 |
Publish date | Sep 17, 2022 (structure data deposition date) |
Authors | Shankar, S. / Ramachandran, S. / Tulsian, N. / Radhakrishnan, S. / Jobichen, C. / Sivaraman, J. |
External links | Febs J. / PubMed:36259273 |
Methods | X-ray diffraction |
Resolution | 2.801 Å |
Structure data | PDB-8gwr: |
Chemicals | ChemComp-HZO: ChemComp-HOH: |
Source |
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Keywords | ONCOPROTEIN / Glutaminase / complex / allosteric inhibition / small molecule inhibitor / cancer |