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-Structure paper
Title | Affinity and cooperativity modulate ternary complex formation to drive targeted protein degradation. |
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Journal, issue, pages | Nat Commun, Vol. 14, Page 4177-4177, Year 2023 |
Publish date | Feb 2, 2023 (structure data deposition date) |
![]() | Wurz, R.P. / Rui, H. / Dellamaggiore, K. / Ghimire-Rijal, S. / Choi, K. / Smither, K. / Amegadzie, A. / Chen, N. / Li, X. / Banerjee, A. ...Wurz, R.P. / Rui, H. / Dellamaggiore, K. / Ghimire-Rijal, S. / Choi, K. / Smither, K. / Amegadzie, A. / Chen, N. / Li, X. / Banerjee, A. / Chen, Q. / Mohl, D. / Vaish, A. |
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Methods | X-ray diffraction |
Resolution | 2.7 - 3.73 Å |
Structure data | ![]() PDB-8g1p: ![]() PDB-8g1q: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-FWZ: ![]() ChemComp-HOH: ![]() ChemComp-NA: ![]() ChemComp-YHB: ![]() ChemComp-PEG: |
Source |
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![]() | GENE REGULATION / Ternary Complex / PROTACs / TRANSCRIPTION |