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-Structure paper
Title | Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib. |
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Journal, issue, pages | Plos One, Vol. 18, Page e0290872-e0290872, Year 2023 |
Publish date | Dec 2, 2022 (structure data deposition date) |
![]() | Lin, D.Y. / Andreotti, A.H. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.7 - 2.6 Å |
Structure data | ![]() PDB-8fd9: ![]() PDB-8ff0: |
Chemicals | ![]() ChemComp-XQQ: ![]() ChemComp-BR: ![]() ChemComp-HOH: ![]() ChemComp-7GB: |
Source |
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![]() | TRANSFERASE/TRANSFERASE INHIBITOR / inhibitor / kinase / complex / covalent / TRANSFERASE-TRANSFERASE INHIBITOR complex |