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Structure paper

TitleCrystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound
Journal, issue, pagesTo be published
Publish dateNov 21, 2022 (structure data deposition date)
AuthorsKimani, S. / Li, A. / Dong, A. / Li, Y. / Hutchinson, A. / Seitova, A. / Wilson, B. / Al-Awar, R. / Vedadi, M. / Brown, P. ...Kimani, S. / Li, A. / Dong, A. / Li, Y. / Hutchinson, A. / Seitova, A. / Wilson, B. / Al-Awar, R. / Vedadi, M. / Brown, P. / Arrowsmith, C.H. / Edwards, A.M. / Halabelian, L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.55 Å
Structure data

PDB-8f8e:
Crystal structure of the WDR domain of human DCAF1 in complex with OICR-8268 compound
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-XJI:
(3P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-3-(4-chloro-2-fluorophenyl)-1H-pyrazole-4-carboxamide

ChemComp-CIT:
CITRIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/INHIBITOR / WD-repeat / WDR / DCAF1 / SGC / TRANSFERASE / Structural Genomics / Structural Genomics Consortium / TRANSFERASE-INHIBITOR complex

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