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Title | PYK-SubstitutionOME: an integrated database containing allosteric coupling, ligand affinity and mutational, structural, pathological, bioinformatic and computational information about pyruvate kinase isozymes. |
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Journal, issue, pages | Database (Oxford), Vol. 2023, Year 2023 |
Publish date | Nov 15, 2022 (structure data deposition date) |
![]() | Swint-Kruse, L. / Dougherty, L.L. / Page, B. / Wu, T. / O'Neil, P.T. / Prasannan, C.B. / Timmons, C. / Tang, Q. / Parente, D.J. / Sreenivasan, S. ...Swint-Kruse, L. / Dougherty, L.L. / Page, B. / Wu, T. / O'Neil, P.T. / Prasannan, C.B. / Timmons, C. / Tang, Q. / Parente, D.J. / Sreenivasan, S. / Holyoak, T. / Fenton, A.W. |
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Methods | X-ray diffraction |
Resolution | 2.15 - 2.41 Å |
Structure data | ![]() PDB-8f5t: ![]() PDB-8f5u: ![]() PDB-8f6m: |
Chemicals | ![]() ChemComp-MG: ![]() ChemComp-NA: ![]() ChemComp-TRS: ![]() ChemComp-GOL: ![]() ChemComp-HOH: ![]() ChemComp-EDO: ![]() ChemComp-K: ![]() ChemComp-PYR: ![]() ChemComp-ADP: ![]() ChemComp-SIN: ![]() ChemComp-MN: ![]() ChemComp-ALA: ![]() ChemComp-GZ3: |
Source |
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![]() | CYTOSOLIC PROTEIN / glycolysis / metabolic kinase / central metabolism |