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| Title | Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy. |
|---|---|
| Journal, issue, pages | J Immunother Cancer, Vol. 10, Year 2022 |
| Publish date | Jul 21, 2022 (structure data deposition date) |
 Authors | Guelen, L. / Fischmann, T.O. / Wong, J. / Mauze, S. / Guadagnoli, M. / Babala, N. / Wagenaars, J. / Juan, V. / Rosen, D. / Prosise, W. ...Guelen, L. / Fischmann, T.O. / Wong, J. / Mauze, S. / Guadagnoli, M. / Babala, N. / Wagenaars, J. / Juan, V. / Rosen, D. / Prosise, W. / Habraken, M. / Lodewijks, I. / Gu, D. / Stammen-Vogelzangs, J. / Yu, Y. / Baker, J. / Lutje Hulsik, D. / Driessen-Engels, L. / Malashock, D. / Kreijtz, J. / Bertens, A. / de Vries, E. / Bovens, A. / Bramer, A. / Zhang, Y. / Wnek, R. / Troth, S. / Chartash, E. / Dobrenkov, K. / Sadekova, S. / van Elsas, A. / Cheung, J.K. / Fayadat-Dilman, L. / Borst, J. / Beebe, A.M. / Van Eenennaam, H. |
 External links | J Immunother Cancer / PubMed:36100308 |
| Methods | X-ray diffraction |
| Resolution | 1.926 Å |
| Structure data |  PDB-8ds5: |
| Chemicals |  ChemComp-CD:  ChemComp-2PE:  ChemComp-HOH: |
| Source |
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 Keywords | IMMUNE SYSTEM / Complex |
homo sapiens (human)
mus musculus (house mouse)