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Structure paper

TitleTBD
Journal, issue, pagesTo Be Published
Publish dateMay 27, 2022 (structure data deposition date)
AuthorsSong, X. / Butler, J. / Li, C. / Zhang, K. / Zhang, D. / Hao, Y.
External linksPubMed:pdb-8d1t
MethodsX-ray diffraction
Resolution2.94 Å
Structure data

PDB-8d1t:
Crystal structure of human USP30 in complex with a covalent inhibitor 552 and a Fab
Method: X-RAY DIFFRACTION / Resolution: 2.94 Å

Chemicals

ChemComp-PXW:
(1R,2R,4S,7E)-7-[amino(sulfanyl)methylidene]-2-{[(1P)-3-chloro-3'-(1-cyanocyclopropyl)[1,1'-biphenyl]-4-carbonyl]amino}-7-azabicyclo[2.2.1]heptan-7-ium

ChemComp-ZN:
Unknown entry

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsHYDROLASE / deubiquitinase / covalent inhibitor

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