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-Structure paper
Title | Inhibitors of the Elastase LasB for the Treatment of Pseudomonas aeruginosa Lung Infections. |
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Journal, issue, pages | Acs Cent. Sci., Vol. 9, Page 2205-2215, Year 2023 |
Publish date | Jan 26, 2023 (structure data deposition date) |
![]() | Konstantinovic, J. / Kany, A.M. / Alhayek, A. / Abdelsamie, A.S. / Sikandar, A. / Voos, K. / Yao, Y. / Andreas, A. / Shafiei, R. / Loretz, B. ...Konstantinovic, J. / Kany, A.M. / Alhayek, A. / Abdelsamie, A.S. / Sikandar, A. / Voos, K. / Yao, Y. / Andreas, A. / Shafiei, R. / Loretz, B. / Schonauer, E. / Bals, R. / Brandstetter, H. / Hartmann, R.W. / Ducho, C. / Lehr, C.M. / Beisswenger, C. / Muller, R. / Rox, K. / Haupenthal, J. / Hirsch, A.K.H. |
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Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | ![]() PDB-8cc4: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-U7F: ![]() ChemComp-ZN: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / LasB / (4-methyl-1-oxo-1-((4-(trifluoromethyl)phenyl)amino)pentan-2-yl)phosphonic acid inhibitor complex |