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-Structure paper
Title | Discovery of Conformationally Constrained ALK2 Inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 67, Page 4707-4725, Year 2024 |
Publish date | Jan 17, 2023 (structure data deposition date) |
![]() | Gonzalez-Alvarez, H. / Ensan, D. / Xin, T. / Wong, J.F. / Zepeda-Velazquez, C.A. / Cros, J. / Sweeney, M.N. / Hoffer, L. / Kiyota, T. / Wilson, B.J. ...Gonzalez-Alvarez, H. / Ensan, D. / Xin, T. / Wong, J.F. / Zepeda-Velazquez, C.A. / Cros, J. / Sweeney, M.N. / Hoffer, L. / Kiyota, T. / Wilson, B.J. / Aman, A. / Roberts, O. / Isaac, M.B. / Bullock, A.N. / Smil, D. / Al-Awar, R. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.23 - 2.26 Å |
Structure data | ![]() PDB-8c7w: ![]() PDB-8c7z: |
Chemicals | ![]() ChemComp-U0C: ![]() ChemComp-SO4: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-NH4: ![]() ChemComp-TZX: |
Source |
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![]() | SIGNALING PROTEIN / BMP signalling Kinase Inhibitor |