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TitleLinked-fragment stabilizers of 14-3-3 protein-protein interactions
Journal, issue, pagesTo Be Published
Publish dateDec 14, 2022 (structure data deposition date)
AuthorsVisser, E.J. / Jaishankar, P. / Sijbesma, E. / Pennings, M.A.M. / Vandenboorn, E.M.F. / Renslo, A. / Arkin, M.R. / Brunsveld, L. / Ottmann, C.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.1 Å
Structure data

PDB-8bzc:
co-soaked stabilizers for ERa - 14-3-3 interaction (884_AZ244)
Method: X-RAY DIFFRACTION / Resolution: 1.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-GEH:
2-(4-chloranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide

ChemComp-SG0:
4-[(~{R})-azanyl(oxidanyl)methyl]-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsSTRUCTURAL PROTEIN / 14-3-3 / ERa / fragment linking / stabilization

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