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-Structure paper
Title | A non-canonical nucleophile unlocks a new mechanistic pathway in a designed enzyme. |
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Journal, issue, pages | Nat Commun, Vol. 15, Page 1956-1956, Year 2024 |
Publish date | Nov 15, 2022 (structure data deposition date) |
![]() | Hutton, A.E. / Foster, J. / Crawshaw, R. / Hardy, F.J. / Johannissen, L.O. / Lister, T.M. / Gerard, E.F. / Birch-Price, Z. / Obexer, R. / Hay, S. / Green, A.P. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.72 - 2.621 Å |
Structure data | ![]() PDB-8bp0: ![]() PDB-8bp1: |
Chemicals | ![]() ChemComp-PGE: ![]() ChemComp-EDO: ![]() ChemComp-HOH: ![]() ChemComp-PEG: ![]() ChemComp-ACT: ![]() ChemComp-MG: ![]() ChemComp-SO4: |
Source |
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![]() | BIOSYNTHETIC PROTEIN / Morita-Baylis-Hillmanase / non-canonical amino acid / methylhistidine / de novo enzyme / Morita-Baylis-Hillman |